| | Jyong Biotech Ltd | Biotechnology | Healthcare | -81.04 | -88.94 | -90.49 | -94.56 | -71.12 | -71.12 | -71.12 | -71.12 |
| | Vistagen Therapeutics Inc | Biotechnology | Healthcare | -80.25 | -80.99 | -80.52 | -70.31 | -63.82 | -64.57 | -83.41 | -73.91 |
| | Sonnet BioTherapeutics Holdings Inc | Biotechnology | Healthcare | -59.35 | -69.71 | -68.73 | -60.25 | 7.69 | -51.72 | -90.28 | -99.33 |
| | Traws Pharma Inc | Biotechnology | Healthcare | -36.36 | -43.32 | -32.69 | -29.65 | -15.66 | -72.39 | -93.46 | -93.46 |
| | Kyverna Therapeutics Inc | Biotechnology | Healthcare | -32.52 | -15.53 | -3.49 | 58.12 | 133.45 | 64.92 | -76.97 | -76.97 |
| | PMGC Holdings Inc | Biotechnology | Healthcare | -29.68 | -46.53 | -55.66 | -59.47 | -67.65 | -95.21 | -99.98 | -99.99 |
| | Zynex Inc | Medical Distribution | Healthcare | -22.43 | -69.76 | -53.32 | -82.41 | -88.82 | -96.86 | -97.44 | -98.06 |
| | 4D Molecular Therapeutics Inc | Biotechnology | Healthcare | -20.05 | -14.96 | -15.89 | 38.29 | 121.93 | 45.73 | -50.83 | -55.51 |
| | Venus Concept Inc | Medical Devices | Healthcare | -19.47 | -1.62 | 5.81 | -22.88 | -25.10 | -47.92 | -82.77 | -96.16 |
| | Soligenix Inc | Biotechnology | Healthcare | -19.08 | -23.13 | -8.89 | -56.23 | -31.67 | -59.27 | -86.02 | -99.22 |
| | Lexaria Bioscience Corp | Biotechnology | Healthcare | -18.86 | -41.24 | -32.51 | -43.67 | -31.84 | -67.23 | -51.66 | -71.83 |
| | Palatin Technologies Inc | Biotechnology | Healthcare | -17.85 | -17.56 | 65.91 | 91.30 | 91.30 | 2,444.58 | 769.14 | 581.29 |
| | NeOnc Technologies Holdings Inc | Biotechnology | Healthcare | -17.06 | -17.14 | -1.63 | -26.20 | 47.74 | -35.34 | -35.34 | -35.34 |
| | Reviva Pharmaceuticals Holdings Inc | Biotechnology | Healthcare | -16.67 | -68.09 | -89.83 | -94.90 | -94.79 | -99.14 | -99.62 | -99.71 |
| | Biodexa Pharmaceuticals Plc ADR | Biotechnology | Healthcare | -16.00 | -18.75 | 0.00 | -19.71 | -31.43 | -86.97 | -99.28 | -99.94 |
| | EDAP TMS S.A. ADR | Medical Distribution | Healthcare | -15.87 | 12.77 | 27.71 | 10.42 | 54.97 | 7.72 | -47.00 | -74.27 |
| | Immunome Inc | Biotechnology | Healthcare | -15.76 | -2.56 | 9.10 | 120.02 | 121.01 | 64.56 | 155.23 | 461.93 |
| | Pyxis Oncology Inc | Biotechnology | Healthcare | -15.75 | -21.45 | -27.53 | 52.49 | 183.19 | 106.75 | 93.68 | 188.03 |
| | CureVac N.V. | Biotechnology | Healthcare | -14.32 | -19.18 | -21.78 | -22.95 | -24.91 | 40.00 | -29.04 | -37.42 |
| | Caring Brands Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -14.13 | -36.49 | -3.96 | -42.43 | -42.43 | -42.43 | -42.43 | -42.43 |
| | Psyence Biomedical Ltd Wt | Biotechnology | Healthcare | -13.89 | -23.27 | -48.16 | -40.38 | -17.99 | 22.05 | -69.00 | -69.00 |
| | Cellectar Biosciences Inc | Biotechnology | Healthcare | -13.84 | -31.84 | -6.16 | -45.85 | -74.01 | -65.19 | -96.39 | -92.81 |
| | CDT Equity Inc Wt | Biotechnology | Healthcare | -13.64 | -12.04 | -18.80 | -24.60 | -24.00 | -5.94 | -81.04 | -85.97 |
| | AirSculpt Technologies Inc | Medical Care Facilities | Healthcare | -13.42 | -26.32 | -46.64 | -64.05 | -55.94 | -64.63 | -69.10 | -27.76 |