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Cyclerion Therapeutics Inc

IEX • Healthcare • Biotechnology • Quote as of 09/08/2026
Cyclerion Therapeutics Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeIEX
Market Capitalization15.73 mln
Earnings Date11/13/2026

Piotroski F-Score

2 / 9
Weak

Beneish M-Score

-5.66
Highly reliable

1-Year Forecast

56.00
Transformational upside

Relative Strength

4 / 100
Severely lagging

Pre-Tax Margin

-353%
Severely loss-making

ROE

-85.83
Deeply negative

Business Description

Cyclerion Therapeutics is a Cambridge, Massachusetts-based drug development company focused on treating serious conditions affecting the heart, kidneys, and nervous system. The company is advancing two key drug candidates: Olinciguat, currently in Phase 2 trials for cardiovascular disease, and Praliciguat, aimed at treating rare kidney conditions. Cyclerion has partnered with Akebia Therapeutics to develop, manufacture, and commercialize Praliciguat and related treatments. Founded in 2018, the company applies its expertise in a specific class of molecules known as sGC stimulators to address diseases with limited treatment options.

Key Fundamentals

EPS-11.62
ROE-85.83
RPS3.43
ROIC-121
ROA-74.18
EBITDA, mln-6.82
EV / EBITDA-2.38
EV / EBIT-2.38
Revenue, mln1.90
EV / Revenue8.53

Financial Strength

Altman Z-Score-52.99
Piotroski F-Score 2 / 9
Beneish M-Score-5.66
1-Year Target Price56.00
Short Ratio2.20
Short % of Float1.33

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week -7.32% 6 / 100   
1 Month -7.82% 18 / 100   
2 Months 11.04% 79 / 100   
6 Months 130% 99 / 100   
1 Year 54.05% 84 / 100   



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