| Cassava Sciences Inc | Biotechnology | Healthcare | -76.11 | -90.33 | -99.18 | -99.61 | -99.05 | -99.05 | -99.05 | -99.05 |
| Lyra Therapeutics Inc | Biotechnology | Healthcare | -3.62 | -90.76 | -92.90 | -92.35 | -87.58 | -85.51 | -92.29 | -95.37 |
| GlycoMimetics Inc | Biotechnology | Healthcare | -10.54 | -85.43 | -89.12 | -91.43 | -77.78 | -84.85 | -58.34 | -87.66 |
| Marinus Pharmaceuticals Inc | Biotechnology | Healthcare | -3.97 | -11.92 | -83.56 | -86.97 | -77.68 | -86.12 | -73.97 | -90.60 |
| Macrogenics Inc | Biotechnology | Healthcare | -77.44 | -78.88 | -81.86 | -81.53 | -48.28 | -54.09 | -28.51 | -89.14 |
| AEON Biopharma Inc | Biotechnology | Healthcare | 4.22 | 1.76 | -79.67 | -80.73 | -58.61 | -81.20 | -81.20 | -81.20 |
| NRX Pharmaceuticals Inc Wt | Biotechnology | Healthcare | -5.33 | -28.93 | -75.93 | -62.13 | 9.23 | -52.67 | -85.80 | -98.11 |
| Eiger BioPharmaceuticals Inc | Biotechnology | Healthcare | -9.21 | 4.55 | -74.48 | -76.78 | -78.78 | -92.83 | -99.27 | -99.30 |
| Cyclacel Pharmaceuticals Inc 6 Conv. Pfd | Biotechnology | Healthcare | -0.94 | -14.29 | -65.76 | -69.57 | 9.46 | -64.36 | 6.81 | -6.82 |
| Addex Therapeutics Ltd ADR | Biotechnology | Healthcare | 4.36 | 4.36 | -65.71 | -9.76 | 66.16 | -50.46 | -88.09 | -95.29 |
| Avenue Therapeutics Inc | Biotechnology | Healthcare | -3.61 | -16.32 | -64.35 | -64.30 | -76.25 | -94.87 | -98.86 | -99.92 |
| Aptevo Therapeutics Inc | Biotechnology | Healthcare | -4.81 | -10.01 | -62.92 | -86.87 | -88.57 | -98.83 | -99.48 | -99.91 |
| Enlivex Therapeutics Ltd | Biotechnology | Healthcare | -1.32 | -7.41 | -62.31 | -47.74 | -16.20 | -47.37 | -64.71 | -84.55 |
| Tevogen Bio Holdings Inc | Biotechnology | Healthcare | -0.70 | 1.49 | -59.82 | -90.16 | -90.16 | -90.16 | -90.16 | -90.16 |
| Calidi Biotherapeutics Inc | Biotechnology | Healthcare | 1.72 | 19.80 | -59.81 | -59.17 | -88.20 | -95.18 | -95.18 | -95.18 |
| Renovaro Inc | Biotechnology | Healthcare | -5.83 | -24.67 | -54.44 | -66.37 | -61.56 | 50.27 | 50.27 | 50.27 |
| TFF Pharmaceuticals Inc | Biotechnology | Healthcare | -10.55 | -3.94 | -52.09 | -73.25 | -65.52 | -88.53 | -98.14 | -99.13 |
| RATherapeutics Inc | Biotechnology | Healthcare | -7.08 | -48.02 | -52.00 | -83.63 | -63.09 | -77.98 | -60.92 | -78.25 |
| NKGen Biotech Inc Wt | Biotechnology | Healthcare | -20.83 | -52.38 | -51.13 | -38.71 | -47.22 | -84.17 | -84.17 | -84.17 |
| Reviva Pharmaceuticals Holdings Inc Wt | Biotechnology | Healthcare | 15.53 | -31.86 | -50.62 | -64.88 | -77.29 | -87.47 | 79.32 | -41.27 |
| Seelos Therapeutics Inc | Biotechnology | Healthcare | -5.03 | -21.01 | -50.32 | -66.89 | -93.84 | -99.03 | -98.38 | -99.82 |
| Mustang Bio Inc | Biotechnology | Healthcare | -3.77 | -18.19 | -49.96 | -80.00 | -83.44 | -94.27 | -97.52 | -99.40 |
| Annovis Bio Inc | Biotechnology | Healthcare | -1.66 | 14.48 | -49.53 | -44.00 | 2.24 | -60.36 | -39.61 | -79.27 |
| Estrella Immunopharma Inc Wt | Biotechnology | Healthcare | -2.50 | -49.86 | -49.20 | -12.25 | -56.13 | -81.53 | -81.53 | -81.53 |