| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | 7.59 | 15.12 | -38.65 | -65.57 | -85.00 | -82.97 | -97.58 | -98.44 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -1.72 | 14.67 | 19.37 | -1.72 | -40.00 | 39.14 | -84.64 | -84.64 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | 2.04 | -1.79 | 24.21 | -0.94 | -6.35 | -34.59 | -60.22 | -79.89 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | -26.91 | -22.03 | -33.12 | -35.45 | -45.80 | -46.52 | -56.11 | -65.13 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | -1.97 | 5.05 | -2.49 | -8.66 | -12.06 | -6.44 | -31.81 | -43.32 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | -0.12 | 1.19 | -8.41 | -15.04 | -30.42 | -44.05 | -61.13 | -41.67 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | 1.01 | -2.23 | 0.86 | 6.04 | -20.59 | 3.39 | -7.14 | -34.94 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 1.01 | 24.15 | 10.00 | -45.00 | -62.20 | -58.36 | -91.54 | -29.58 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | -1.18 | 1.89 | -15.79 | -16.35 | -6.66 | 17.73 | -20.64 | -25.45 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | -1.18 | -0.30 | 0.79 | 2.52 | -1.99 | 5.45 | 0.44 | -5.53 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | -2.76 | 3.33 | 2.32 | 12.25 | 7.41 | -5.29 | 15.86 | -2.52 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | -2.28 | 4.28 | -4.43 | -15.84 | -16.91 | -33.44 | -24.30 | 3.51 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | -1.78 | 1.38 | -2.88 | 2.37 | 0.14 | -5.84 | 0.01 | 13.06 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | -1.55 | 1.05 | -0.44 | 1.41 | 1.56 | 11.42 | 10.70 | 15.88 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -1.28 | 4.74 | -3.57 | -19.72 | -40.72 | -48.45 | -19.48 | 20.01 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | -2.45 | 1.41 | -7.54 | -0.97 | -9.67 | 5.43 | 26.52 | 35.06 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | -1.90 | 0.14 | 1.57 | 7.99 | 4.16 | 16.82 | 13.80 | 35.11 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | -0.90 | 7.19 | -5.40 | 2.62 | -3.23 | 23.89 | 35.64 | 46.47 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | 2.76 | 9.07 | 9.09 | 69.41 | 63.02 | 63.02 | 63.02 | 63.02 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | -3.09 | -2.73 | -7.22 | 5.69 | 17.14 | 63.53 | 36.75 | 92.43 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -11.66 | -7.63 | -1.38 | -1.87 | -2.73 | 2.87 | 98.56 | 181.81 |
