| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | 2.82 | 16.75 | -45.50 | -69.22 | -85.62 | -84.13 | -97.75 | -98.55 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 22.77 | 19.28 | 8.90 | -48.14 | -62.45 | -59.29 | -91.62 | -30.28 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | 3.57 | 25.95 | 18.37 | -7.94 | -47.27 | 36.49 | -84.37 | -84.37 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | 1.98 | 8.40 | -4.31 | -21.24 | -40.65 | -47.42 | -18.43 | 21.57 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | 0.76 | 2.46 | -11.52 | -17.20 | -33.17 | -43.64 | -61.08 | -41.60 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | -1.75 | 12.53 | -13.16 | -17.55 | -25.26 | -25.97 | -39.95 | -52.30 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | -1.84 | -3.34 | -2.25 | 0.58 | -20.75 | 8.09 | -8.07 | -35.59 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | 0.58 | 8.20 | -5.08 | -13.15 | -17.37 | -32.11 | -22.53 | 5.92 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | 2.61 | 9.02 | -3.67 | -9.29 | -11.64 | 1.25 | -30.44 | -42.18 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | 4.16 | 3.86 | 20.06 | -7.50 | -10.66 | -41.58 | -61.01 | -80.29 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | 0.82 | 4.69 | -6.62 | 3.26 | -6.31 | 9.44 | 29.71 | 38.46 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | 1.99 | 3.44 | -16.80 | -14.20 | -2.57 | 19.86 | -19.69 | -24.57 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | 0.82 | 10.19 | -6.02 | 12.10 | -1.36 | 24.32 | 36.88 | 47.80 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 0.26 | 0.60 | -5.75 | 3.07 | -1.11 | 11.57 | 1.64 | -4.40 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 0.11 | 4.79 | -2.33 | 2.21 | -0.02 | -3.46 | 1.83 | 15.11 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | 2.29 | 3.64 | -0.92 | 1.48 | 2.81 | 15.01 | 12.44 | 17.70 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | 0.04 | 3.05 | 1.80 | 10.85 | 5.64 | 19.54 | 16.01 | 37.73 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | 1.55 | 8.38 | 8.84 | 9.36 | 6.49 | 15.81 | 124.77 | 219.02 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | 2.26 | 7.62 | 2.87 | 13.93 | 10.07 | 0.05 | 19.15 | 0.25 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | 2.24 | 0.15 | -4.92 | 10.66 | 22.54 | 69.54 | 41.11 | 98.56 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | 4.84 | 7.24 | 13.01 | 54.56 | 58.64 | 58.64 | 58.64 | 58.64 |
