| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | -4.50 | -13.77 | -30.63 | -20.03 | 70.28 | -26.55 | -81.71 | -95.95 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | -4.14 | -10.90 | -24.04 | -39.30 | -53.20 | -46.12 | -47.55 | -47.55 |
| | Medicus Pharma Ltd Wt | Drug Manufacturers - General | Healthcare | 0.00 | 0.34 | -14.57 | -14.34 | 1.23 | -34.40 | 36.78 | 36.78 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 0.00 | 63.25 | -7.17 | 19.93 | 71.33 | -26.57 | -63.79 | -69.64 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | -2.32 | -3.29 | -4.70 | -4.19 | 17.13 | 29.69 | 42.64 | 56.80 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | -0.44 | -9.37 | -4.08 | 17.34 | 32.21 | 19.55 | -31.53 | -41.79 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -3.76 | -4.81 | -2.75 | 25.15 | 34.34 | 39.33 | 65.03 | 195.62 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | 1.21 | 2.37 | -2.04 | 8.02 | 8.90 | 5.89 | 4.03 | -33.77 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | -3.35 | -5.90 | -1.11 | -6.88 | -7.37 | 21.14 | 23.46 | -0.34 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | -0.88 | -1.37 | -0.73 | -3.04 | -1.35 | -0.79 | -2.11 | 7.49 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | -3.29 | -2.19 | -0.24 | 13.18 | 32.43 | 56.13 | 33.45 | 55.66 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | -2.26 | 0.49 | 1.24 | 3.18 | 12.70 | 34.93 | 50.88 | 57.77 |
| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -1.35 | -2.01 | 1.39 | 10.61 | -12.05 | 22.69 | 60.44 | -80.32 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | 0.32 | -0.02 | 1.45 | 11.79 | 14.55 | 26.71 | 15.68 | 34.82 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 0.47 | 6.72 | 2.52 | 15.59 | 43.45 | 56.10 | 45.44 | 39.56 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | -2.44 | -0.02 | 2.65 | 10.80 | 34.57 | 46.14 | 45.70 | 41.49 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | -0.73 | -9.15 | 5.37 | -25.39 | -5.58 | 31.98 | -32.88 | -62.18 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | -0.70 | 1.29 | 5.52 | 31.37 | 25.08 | 6.39 | 24.91 | -10.23 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | -2.06 | 1.19 | 5.89 | 10.14 | 19.62 | 47.83 | 39.33 | 64.83 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | -0.04 | -0.02 | 10.68 | 33.06 | 38.65 | 15.04 | -0.17 | 10.09 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -3.04 | -0.38 | 13.40 | 0.71 | -14.35 | -29.77 | -44.64 | -14.19 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | 1.05 | 7.01 | 23.93 | -8.66 | -8.56 | -43.27 | -42.86 | -68.59 |
