| | MIRA Pharmaceuticals Inc | Drug Manufacturers - General | Healthcare | -10.00 | 28.57 | 25.58 | -19.80 | 72.54 | 48.62 | -48.73 | -78.17 |
| | Scilex Holding Co | Drug Manufacturers - General | Healthcare | -3.95 | -14.40 | -48.80 | 38.16 | 112.29 | -61.43 | -79.94 | -96.09 |
| | Novo Nordisk A/S ADR | Drug Manufacturers - General | Healthcare | -3.07 | -4.50 | -6.58 | -16.07 | -5.65 | -53.11 | -44.60 | 7.09 |
| | Medicus Pharma Ltd Wt | Drug Manufacturers - General | Healthcare | -2.99 | -2.99 | 7.79 | -19.16 | 26.98 | 45.64 | 45.64 | 45.64 |
| | Amarin Corp Plc ADR | Drug Manufacturers - General | Healthcare | -2.14 | 7.73 | 34.52 | 24.38 | 115.59 | 72.28 | 23.52 | -14.61 |
| | Medicus Pharma Ltd | Drug Manufacturers - General | Healthcare | -2.07 | -4.84 | -2.07 | -27.38 | -41.00 | -10.94 | -10.94 | -10.94 |
| | Eli Lilly & Co | Drug Manufacturers - General | Healthcare | -2.02 | -3.68 | 5.62 | 5.66 | -4.01 | -11.81 | 33.85 | 147.33 |
| | Organon & Co | Drug Manufacturers - General | Healthcare | -1.07 | -3.33 | -11.20 | -3.53 | -16.18 | -45.23 | -37.12 | -54.45 |
| | Grifols S.A. ADR | Drug Manufacturers - General | Healthcare | -1.03 | 3.54 | -1.03 | -2.69 | 38.12 | 13.84 | 11.51 | 55.22 |
| | GSK Plc ADR | Drug Manufacturers - General | Healthcare | 0.32 | 0.85 | 8.80 | 21.71 | 24.93 | 17.79 | 29.89 | 58.24 |
| | Novartis AG ADR | Drug Manufacturers - General | Healthcare | 0.50 | 1.08 | 7.32 | 14.77 | 18.55 | 15.41 | 42.77 | 80.92 |
| | Biogen Inc | Drug Manufacturers - General | Healthcare | 0.52 | -2.44 | -1.29 | 11.12 | 20.56 | -24.56 | -46.53 | -46.95 |
| | Bristol Myers Squibb Co | Drug Manufacturers - General | Healthcare | 0.55 | -0.75 | -4.16 | -7.97 | -8.97 | -13.88 | -16.13 | -30.19 |
| | Johnson & Johnson | Drug Manufacturers - General | Healthcare | 0.57 | 1.31 | 9.04 | 19.42 | 24.66 | 21.28 | 31.83 | 27.08 |
| | Amgen Inc | Drug Manufacturers - General | Healthcare | 1.01 | 2.99 | 8.77 | 1.00 | 9.60 | -3.90 | 11.84 | 29.99 |
| | AstraZeneca Plc ADR | Drug Manufacturers - General | Healthcare | 1.03 | 0.19 | 9.01 | 23.11 | 26.15 | 10.85 | 27.48 | 60.53 |
| | Merck & Co Inc | Drug Manufacturers - General | Healthcare | 1.04 | -1.40 | 4.50 | 5.04 | 10.88 | -19.88 | -13.35 | -1.48 |
| | Pfizer Inc | Drug Manufacturers - General | Healthcare | 1.16 | -1.09 | 1.91 | 1.44 | 14.76 | -10.39 | -15.18 | -34.40 |
| | AbbVie Inc | Drug Manufacturers - General | Healthcare | 1.19 | 0.31 | 4.72 | 20.81 | 34.82 | 26.00 | 65.09 | 77.43 |
| | Sanofi ADR | Drug Manufacturers - General | Healthcare | 1.20 | 5.26 | 7.77 | 4.05 | 2.62 | -4.79 | 0.06 | 41.24 |
| | Gilead Sciences Inc | Drug Manufacturers - General | Healthcare | 4.21 | 4.80 | 9.40 | 13.66 | 19.13 | 44.77 | 63.68 | 105.95 |
| | Scilex Holding Co Wt | Drug Manufacturers - General | Healthcare | 12.00 | -3.93 | -61.49 | -57.67 | 167.73 | -55.20 | -76.88 | -13.96 |
