| | CASI Pharmaceuticals Inc | Biotechnology | Healthcare | -74.06 | -73.37 | -78.83 | -81.64 | -91.46 | -91.09 | -96.19 | -88.96 |
| | BriaCell Therapeutics Corp Wt | Biotechnology | Healthcare | -57.14 | -85.00 | -94.00 | -97.86 | -95.71 | -99.19 | -99.94 | -99.97 |
| | Abpro Corp | Biotechnology | Healthcare | -34.76 | -28.98 | -83.11 | -91.81 | -92.96 | -98.15 | -99.65 | -99.65 |
| | Ginkgo Bioworks Holdings Inc | Biotechnology | Healthcare | -30.48 | -26.79 | -30.48 | -27.26 | -45.34 | -21.88 | -88.97 | -88.44 |
| | Celularity Inc Wt | Biotechnology | Healthcare | -28.57 | -22.22 | -62.16 | -71.54 | -86.22 | -84.44 | -87.91 | -91.46 |
| | Puma Biotechnology Inc | Biotechnology | Healthcare | -25.00 | -16.54 | -13.24 | 12.87 | 11.76 | 90.64 | -11.76 | 45.04 |
| | Acrivon Therapeutics Inc | Biotechnology | Healthcare | -17.93 | -1.31 | -23.74 | -36.02 | 11.03 | -71.72 | -70.96 | -92.05 |
| | Seer Inc Cl A | Biotechnology | Healthcare | -17.31 | -13.13 | -9.95 | -10.42 | -16.50 | -21.82 | -3.91 | -56.01 |
| | Anebulo Pharmaceuticals Inc | Biotechnology | Healthcare | -16.49 | -23.89 | -60.44 | -84.62 | -86.21 | -70.00 | -87.05 | -88.31 |
| | NRX Pharmaceuticals Inc Wt | Biotechnology | Healthcare | -15.50 | -12.09 | -42.91 | -62.44 | -57.75 | -67.42 | -69.30 | -90.35 |
| | Adlai Nortye Ltd ADR | Biotechnology | Healthcare | -14.47 | -20.77 | 118.33 | 394.34 | 365.09 | 247.79 | 9.93 | -47.60 |
| | Moolec Science S.A. | Biotechnology | Healthcare | -13.19 | -19.00 | 98.80 | 121.67 | -32.83 | -87.72 | -94.63 | -98.84 |
| | Alpha Tau Medical Ltd Wt | Biotechnology | Healthcare | -11.68 | 8.04 | 26.70 | 255.88 | 317.24 | 335.41 | 332.14 | 202.50 |
| | Pasithea Therapeutics Corp Wt | Biotechnology | Healthcare | -11.30 | -15.00 | -19.05 | -22.73 | -45.74 | -58.87 | -5.56 | -59.20 |
| | Purple Biotech Ltd ADR | Biotechnology | Healthcare | -11.16 | -10.64 | -30.61 | -46.45 | -80.07 | -84.48 | -96.70 | -98.89 |
| | ALX Oncology Holdings Inc | Biotechnology | Healthcare | -10.21 | -13.88 | 40.67 | 54.01 | 75.83 | 97.20 | -87.14 | -68.41 |
| | Cingulate Inc Wt | Biotechnology | Healthcare | -9.91 | -11.54 | -64.42 | 2.89 | -21.96 | 20.31 | 179.29 | -87.97 |
| | Lyra Therapeutics Inc | Biotechnology | Healthcare | -9.82 | -30.34 | -40.41 | -72.63 | -85.62 | -90.04 | -99.63 | -99.13 |
| | Hyperion DeFi Inc | Biotechnology | Healthcare | -9.62 | -14.29 | -22.74 | -37.47 | -59.13 | -80.36 | -80.36 | -80.36 |
| | Novavax Inc | Biotechnology | Healthcare | -9.38 | 10.22 | 3.26 | 43.83 | 33.77 | 43.63 | 68.44 | 16.96 |
| | Humacyte Inc | Biotechnology | Healthcare | -9.35 | -1.33 | 8.25 | -17.41 | -27.12 | -66.91 | -75.39 | -62.83 |
| | CervoMed Inc | Biotechnology | Healthcare | -9.32 | -13.82 | -33.50 | -59.86 | -57.51 | 83.03 | -69.73 | -47.43 |
| | WAVE Life Sciences Ltd | Biotechnology | Healthcare | -9.31 | 3.26 | 4.27 | 79.51 | 38.19 | 31.91 | 173.14 | 227.76 |
| | Quince Therapeutics Inc | Biotechnology | Healthcare | -9.24 | -16.26 | -96.20 | -96.56 | -91.94 | -90.96 | -90.48 | -86.60 |
