| | Universe Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -7.17 | -16.69 | -9.92 | 16.35 | -7.58 | -97.46 | -99.35 | -99.90 |
| | Shuttle Pharmaceuticals Holdings Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -6.77 | -7.37 | -32.95 | -20.39 | -59.32 | -92.78 | -97.17 | -99.27 |
| | Incannex Healthcare Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -4.12 | -5.17 | -23.66 | -23.68 | 159.08 | -86.85 | -92.27 | -97.84 |
| | RedHill Biopharma Ltd ADR | Drug Manufacturers - Specialty & Generic | Healthcare | -13.39 | -28.10 | -44.72 | -8.71 | -47.49 | -86.16 | -87.24 | -99.83 |
| | Flora Growth Corp | Drug Manufacturers - Specialty & Generic | Healthcare | 6.35 | -19.35 | -52.55 | -56.31 | -56.62 | -83.97 | -72.35 | -97.69 |
| | Canopy Growth Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -5.83 | -12.40 | -18.71 | 2.73 | -11.02 | -79.42 | -80.60 | -96.57 |
| | cbdMD Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.80 | -21.46 | -37.77 | -8.02 | -44.62 | -78.02 | -85.76 | -99.23 |
| | Rockwell Medical Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.70 | -7.14 | -14.05 | 4.84 | -12.61 | -73.26 | -46.11 | 15.56 |
| | Alvotech Wt | Drug Manufacturers - Specialty & Generic | Healthcare | -23.42 | -52.78 | -35.23 | -35.11 | -34.11 | -71.76 | -50.00 | 30.77 |
| | Akanda Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -6.69 | -24.48 | -47.30 | -54.36 | -61.55 | -68.27 | -98.61 | -99.76 |
| | BioAge Labs Inc | Drug Manufacturers - Specialty & Generic | Healthcare | 0.67 | -5.32 | 32.68 | 69.00 | 80.00 | -66.90 | -59.20 | -59.20 |
| | InMed Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -6.49 | -13.50 | -22.77 | -27.00 | -42.72 | -64.40 | -79.84 | -96.54 |
| | China SXT Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | 0.71 | 7.58 | -13.41 | -10.13 | 0.71 | -62.94 | -92.11 | -98.89 |
| | Alvotech | Drug Manufacturers - Specialty & Generic | Healthcare | -3.98 | -38.63 | -43.71 | -45.55 | -42.02 | -62.62 | -43.90 | -20.17 |
| | Evolus Inc | Drug Manufacturers - Specialty & Generic | Healthcare | 0.31 | -8.95 | -0.31 | -29.64 | -46.63 | -60.96 | -19.57 | -15.55 |
| | Gelteq Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -2.68 | -10.66 | -12.80 | -34.73 | -34.73 | -57.42 | -62.93 | -62.93 |
| | Ironwood Pharmaceuticals Inc Cl A | Drug Manufacturers - Specialty & Generic | Healthcare | 0.54 | 21.43 | 26.35 | 149.17 | 101.57 | -55.37 | -79.67 | -83.55 |
| | SCYNEXIS Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -1.35 | -11.87 | -20.07 | -9.48 | -34.98 | -52.27 | -64.20 | -71.74 |
| | Zhengye Biotechnology Holding Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -7.11 | 1.83 | -22.92 | -61.46 | -82.67 | -50.67 | -50.67 | -50.67 |
| | Amphastar Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -0.16 | 4.47 | -4.97 | 18.04 | 0.56 | -50.07 | -46.06 | -15.12 |
| | Lantheus Holdings Inc | Drug Manufacturers - Specialty & Generic | Healthcare | 1.57 | 0.66 | 9.51 | -19.24 | -46.55 | -50.01 | -10.42 | -4.77 |
| | Cardiol Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -4.11 | -10.26 | -2.78 | -17.97 | -8.70 | -44.74 | 26.51 | 78.88 |
| | Anika Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -1.93 | -1.13 | 4.00 | 9.81 | -33.54 | -43.59 | -54.58 | -67.75 |
| | PainReform Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -9.48 | -19.85 | -24.46 | -22.15 | -54.15 | -43.13 | -98.30 | -99.15 |