| | Emergent Biosolutions Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -7.03 | 2.09 | 0.47 | 29.07 | -23.22 | -9.03 | -24.76 | -80.55 |
| | BGM Group Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -6.63 | -8.42 | -16.12 | 4.91 | 34.49 | 121.26 | 121.26 | 121.26 |
| | Zhengye Biotechnology Holding Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -6.24 | -28.92 | -22.78 | 22.41 | 46.89 | 46.89 | 46.89 | 46.89 |
| | SCYNEXIS Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -6.14 | -5.84 | -5.30 | -31.55 | -30.81 | -65.95 | -75.04 | -64.91 |
| | Ironwood Pharmaceuticals Inc Cl A | Drug Manufacturers - Specialty & Generic | Healthcare | -6.08 | 4.18 | 17.39 | -49.94 | -83.58 | -88.21 | -93.09 | -93.70 |
| | IM Cannabis Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -4.86 | -4.51 | 41.44 | 51.14 | 8.40 | -2.06 | -49.33 | -93.61 |
| | TherapeuticsMD Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -4.27 | 2.75 | -24.83 | 6.67 | 2.75 | -35.63 | -72.00 | -88.71 |
| | Cardiol Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -4.08 | 13.71 | 21.55 | 41.91 | 7.63 | -29.50 | 78.48 | -13.23 |
| | Biofrontera Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.73 | -1.70 | -5.85 | -29.03 | -45.80 | -33.16 | -94.22 | -98.46 |
| | Gelteq Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -3.72 | 13.13 | 0.56 | 66.79 | -27.02 | -38.44 | -38.44 | -38.44 |
| | Universe Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.69 | -7.12 | -21.51 | -31.90 | -85.33 | -99.76 | -99.75 | -99.84 |
| | BioAge Labs Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.67 | -3.23 | 6.33 | 8.25 | -23.64 | -77.06 | -77.06 | -77.06 |
| | Organigram Global Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.57 | 4.65 | 1.12 | 27.36 | -16.67 | -15.63 | -13.46 | -69.04 |
| | BioCryst Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.11 | -7.33 | -13.25 | 19.54 | 21.40 | 53.19 | 32.77 | -13.97 |
| | Cumberland Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.99 | -40.23 | -51.31 | -37.05 | 12.07 | 71.05 | 67.74 | 26.21 |
| | Alvotech | Drug Manufacturers - Specialty & Generic | Healthcare | -2.97 | -2.25 | -19.33 | -11.78 | -27.86 | -23.83 | 22.68 | -0.22 |
| | Flora Growth Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -2.88 | -7.41 | -9.09 | -8.82 | -40.20 | -36.19 | -77.41 | -95.75 |
| | Tilray Brands Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.84 | 11.31 | -9.61 | -43.88 | -71.98 | -76.84 | -74.96 | -88.99 |
| | Incannex Healthcare Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.77 | -7.21 | -24.70 | -70.96 | -89.57 | -92.36 | -97.22 | -98.86 |
| | PainReform Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -2.76 | -12.15 | -25.79 | -42.45 | -59.71 | -88.21 | -98.80 | -99.45 |
| | Esperion Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.59 | -7.14 | 21.19 | -38.29 | -56.42 | -56.99 | -28.00 | -84.83 |
| | Aurora Cannabis Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.58 | 1.72 | -24.13 | -10.17 | -3.49 | -12.26 | -22.09 | -73.23 |
| | Akebia Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.41 | -0.82 | 25.00 | 89.12 | 87.18 | 268.99 | 292.47 | 875.94 |
| | Kamada Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -2.41 | 7.08 | 10.94 | 12.88 | 34.08 | 57.20 | 43.94 | 76.24 |
