| | Cyclo Therapeutics Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -45.85 | -68.00 | -86.61 | -77.14 | -66.80 | -86.58 | -89.33 | -98.04 |
| | Biofrontera Inc Wt | Drug Manufacturers - Specialty & Generic | Healthcare | -18.29 | -28.98 | -57.11 | -45.94 | -50.44 | -45.67 | -88.76 | -97.28 |
| | Gelteq Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -11.85 | -19.83 | 95.79 | -15.45 | -25.00 | -36.73 | -36.73 | -36.73 |
| | Incannex Healthcare Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -10.08 | -78.74 | -80.46 | -92.78 | -94.87 | -95.02 | -98.39 | -99.51 |
| | Petros Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -10.00 | -78.91 | -87.14 | -95.93 | -96.82 | -98.36 | -99.75 | -99.90 |
| | China Pharma Holdings Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -7.91 | 20.10 | -19.20 | -11.09 | -22.81 | -32.33 | -90.34 | -98.63 |
| | Emergent Biosolutions Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -7.87 | -8.38 | 3.80 | -53.10 | -46.05 | 154.92 | -44.53 | -85.44 |
| | Journey Medical Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -7.28 | -8.99 | 15.24 | 42.15 | 11.51 | 96.01 | 338.22 | 80.58 |
| | Sonoma Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -6.84 | -8.29 | 63.13 | 37.21 | 26.88 | 15.54 | -81.75 | -93.35 |
| | cbdMD Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -6.07 | -19.88 | -38.65 | -66.50 | -55.49 | -78.03 | -89.52 | -99.31 |
| | Akanda Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -5.26 | 6.79 | -9.35 | -14.86 | -15.88 | -86.49 | -98.41 | -99.98 |
| | China SXT Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -5.13 | 40.51 | -13.62 | -29.84 | -47.64 | -72.79 | -96.17 | -99.74 |
| | PainReform Ltd | Drug Manufacturers - Specialty & Generic | Healthcare | -4.96 | -0.86 | 2.68 | -23.84 | 27.81 | -89.86 | -98.55 | -98.98 |
| | Durect Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -3.33 | -17.14 | -27.68 | -22.69 | -56.72 | -40.02 | -86.19 | -86.51 |
| | Avadel Pharmaceuticals Plc | Drug Manufacturers - Specialty & Generic | Healthcare | -3.15 | 0.12 | 14.65 | 8.03 | -42.79 | -52.98 | -26.60 | 71.51 |
| | United Therapeutics Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -3.05 | -0.87 | -4.25 | -17.13 | -21.43 | 15.17 | 26.60 | 63.41 |
| | RedHill Biopharma Ltd ADR | Drug Manufacturers - Specialty & Generic | Healthcare | -2.49 | -7.33 | -15.69 | -63.44 | -73.68 | -80.93 | -96.15 | -99.87 |
| | Dynavax Technologies Corp | Drug Manufacturers - Specialty & Generic | Healthcare | -2.30 | 5.32 | -9.68 | -11.28 | -2.55 | -1.71 | 9.13 | 23.44 |
| | Ironwood Pharmaceuticals Inc Cl A | Drug Manufacturers - Specialty & Generic | Healthcare | -2.19 | 3.78 | -35.33 | -56.47 | -78.24 | -88.91 | -91.45 | -92.47 |
| | Amphastar Pharmaceuticals Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -2.17 | -0.79 | -15.59 | -28.48 | -52.93 | -43.25 | -35.94 | -32.37 |
| | Perrigo Co Plc | Drug Manufacturers - Specialty & Generic | Healthcare | -1.75 | 1.53 | -8.77 | 1.75 | -1.21 | -20.10 | -27.48 | -16.19 |
| | Organigram Global Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -1.72 | -1.72 | 9.62 | -21.38 | -34.10 | -40.47 | -41.86 | -80.87 |
| | Takeda Pharmaceutical Co Ltd ADR | Drug Manufacturers - Specialty & Generic | Healthcare | -1.70 | -0.53 | 0.87 | 15.89 | 10.00 | 16.42 | -7.72 | 5.97 |
| | SIGA Technologies Inc | Drug Manufacturers - Specialty & Generic | Healthcare | -1.63 | -7.46 | 9.43 | 3.75 | -16.83 | -35.62 | 10.61 | -3.10 |
