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Spero Therapeutics Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 10/23/2026
Spero Therapeutics Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization71.05 mln
Float42.98 mln
Earnings Date11/16/2026

EPS

0.14
Marginal

P / E

7.93
Undervalued

Piotroski F-Score

7 / 9
Strong

Relative Strength

29 / 100
Underperforming

Debt / Equity

0.05
Debt-free

Pre-Tax Margin

18%
Healthy margin

Business Description

Founded in 2013 and based in Cambridge, Massachusetts, Spero Therapeutics is a clinical-stage company working to develop new medicines for bacterial infections that no longer respond to standard antibiotics, as well as certain rare conditions. Its two leading drug candidates are tebipenem HBr, an oral antibiotic for urinary tract infections currently in late-stage trials, and SPR720, an early treatment option for a serious lung disease caused by nontuberculous mycobacteria. The company works alongside partners including Meiji Seika Pharma, Everest Medicines, and Vertex Pharmaceuticals to advance its pipeline.

Key Fundamentals

EPS0.14
P/E7.93
ROE17.13
RPS0.82
ROIC17.21
ROA12.43
EBITDA, mln7.64
EV / EBITDA2.94
EV / EBIT2.94
Revenue, mln42.96
EV / Revenue0.52

Quote Details

Last 1.11
Change -0.02 (-1.77%)
Open 1.13
Volume 316,175
Turnover 350,954
Average Volume 479,262

Financial Ratios

Pre-Tax Profit Margin18
Leverage Ratio1.19
Current Ratio6.12
Price / Book1.62
Price / Tangible Book1.62
Price / Cash Flow3.61
Price / Free Cash Flow3.47
Debt / Equity0.05
Price / Sales1.69

Financial Strength

Altman Z-Score-5.24
Piotroski F-Score 7 / 9
Price to Graham Number0.87
Short Ratio1.06
Short % of Float1.64

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week 0.91% 70 / 100   
1 Month -11.2% 28 / 100   
2 Months -22.92% 21 / 100   
6 Months -59.49% 9 / 100   
1 Year -50.67% 18 / 100   



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