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Spero Therapeutics Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 08/07/2026
Spero Therapeutics Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization72.96 mln
Float46.38 mln
Earnings Date08/12/2026

EPS

0.27
Marginal

P / E

4.67
Deeply undervalued

Piotroski F-Score

6 / 9
Solid

Beneish M-Score

-1.4
Manipulation likely

Relative Strength

72 / 100
Outperforming

Debt / Equity

0.05
Debt-free

Business Description

Founded in 2013 and based in Cambridge, Massachusetts, Spero Therapeutics is a clinical-stage company working to develop new medicines for bacterial infections that no longer respond to standard antibiotics, as well as certain rare conditions. Its two leading drug candidates are tebipenem HBr, an oral antibiotic for urinary tract infections currently in late-stage trials, and SPR720, an early treatment option for a serious lung disease caused by nontuberculous mycobacteria. The company works alongside partners including Meiji Seika Pharma, Everest Medicines, and Vertex Pharmaceuticals to advance its pipeline.

Key Fundamentals

EPS0.27
P/E4.67
ROE37.14
RPS0.85
ROIC90.77
ROA23.66
EBITDA, mln14.18
EV / EBITDA1.03
EV / EBIT1.03
Revenue, mln54.77
EV / Revenue0.27

Financial Strength

Altman Z-Score-1.28
Piotroski F-Score 6 / 9
Beneish M-Score-1.4
Price to Graham Number0.56
Short Ratio0.97
Short % of Float4.41

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week 7.69% 79 / 100   
1 Month -40.57% 3 / 100   
2 Months -49.8% 6 / 100   
6 Months -45.22% 9 / 100   
1 Year -44.25% 16 / 100   



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