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Senti Biosciences Holdings Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 10/23/2026
Senti Biosciences Holdings Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization5.87 mln
Float8.04 mln
Earnings Date11/13/2026

Piotroski F-Score

3 / 9
Below average

Relative Strength

3 / 100
Severely lagging

Pre-Tax Margin

-90,116%
Severely loss-making

ROE

-660
Deeply negative

Altman Z-Score

-20.76
Deeply distressed

ROA

-102
Deeply negative

Business Description

Senti Biosciences is a clinical-stage biotech company focused on developing advanced cell and gene therapies for patients with serious, hard-to-treat diseases. Its core technology uses specially engineered natural killer cells drawn from healthy donors, which are then equipped with gene circuit systems designed to more precisely target cancer cells while protecting healthy tissue. The company's lead programs, SENTI-202 and SENTI-301A, address blood cancers and liver tumors respectively, and it has partnered with Celest Therapeutics in Shanghai to advance its solid tumor treatment into clinical trials. Founded in 2016 and based in South San Francisco, Senti Biosciences also maintains a broader pipeline of early-stage programs spanning additional cancer treatments and regenerative medicine.

Key Fundamentals

EPS-1.72
ROE-660
RPS0.00
ROIC-148
ROA-102
EBITDA, mln-46.41
EV / EBITDA-0.51
EV / EBIT-0.47
Revenue, mln0.05
EV / Revenue427

Quote Details

Last 0.1884
Change -0.0021 (-1.1%)
Open 0.185
Volume 366,238
Turnover 68,999
Average Volume 773,835

Financial Ratios

Pre-Tax Profit Margin-90,116
Current Ratio0.83
Price / Sales104

Financial Strength

Altman Z-Score-20.76
Piotroski F-Score 3 / 9
Short Ratio0.47
Short % of Float2.74

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week -16.23% 9 / 100   
1 Month -45.07% 4 / 100   
2 Months -56.57% 6 / 100   
6 Months -82.72% 3 / 100   
1 Year -90.48% 3 / 100   



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