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Septerna Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 10/23/2026
Septerna Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization1,906.29 mln
Float29.77 mln
Earnings Date11/25/2026

Piotroski F-Score

6 / 9
Solid

Beneish M-Score

115
Highly suspicious

Relative Strength

89 / 100
Strongly outperforming

Debt / Equity

0.06
Debt-free

Pre-Tax Margin

-23%
Deeply loss-making

ROE

-6.33
Negative

Business Description

Septerna is a clinical-stage biotech company focused on developing oral pill-based medicines that work through a class of cell receptors known as GPCRs. Its current pipeline targets conditions such as hypoparathyroidism, chronic hives, Graves' disease, and thyroid eye disease, with additional research underway in areas like heart health, women's health, and neurology. The company also holds a partnership with Novo Nordisk to discover and bring to market oral treatments for metabolic diseases. Founded in 2019 and based in South San Francisco, California, Septerna operates across multiple therapeutic areas with the goal of addressing diseases that currently lack effective oral treatment options.

Key Fundamentals

EPS-0.54
ROE-6.33
RPS2.21
ROIC-27.14
ROA-4.39
EBITDA, mln-21.26
EV / EBITDA-68.45
EV / EBIT-63.53
Revenue, mln98.88
EV / Revenue14.72

Quote Details

Last 40.41
Change -0.47 (-1.15%)
Open 40.63
Volume 200,302
Turnover 8,094,204
Average Volume 398,629

Financial Ratios

Pre-Tax Profit Margin-23
Leverage Ratio1.47
Current Ratio5.00
Price / Book4.62
Price / Tangible Book4.62
Price / Cash Flow17.28
Price / Free Cash Flow17.21
Debt / Equity0.06
Price / Sales17.82

Financial Strength

Altman Z-Score6.33
Piotroski F-Score 6 / 9
Beneish M-Score115
Short Ratio9.18
Short % of Float12.68

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week 11.17% 95 / 100   
1 Month 5.98% 89 / 100   
2 Months 25.46% 94 / 100   
6 Months 63.8% 97 / 100   
1 Year 83.68% 96 / 100   



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