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Protagonist Therapeutics Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 10/23/2026
Protagonist Therapeutics Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization9,028.75 mln
Float61.22 mln
Earnings Date11/05/2026

EPS

1.03
Stretched

P / E

134
Highly speculative

Piotroski F-Score

8 / 9
Very strong

Beneish M-Score

-2.97
Likely reliable

1-Year Forecast

178.57
Strong upside

Relative Strength

40 / 100
Slightly lagging

Business Description

Protagonist Therapeutics is a US-based drug discovery and development company focused on creating novel treatments for blood disorders, skin conditions, and obesity. Its most advanced programs include Rusfertide, an injectable treatment in late-stage trials for the rare blood disorder polycythemia vera, and Icotyde, an oral peptide therapy for moderate-to-severe plaque psoriasis. The company has several additional candidates in earlier stages of development targeting conditions such as atopic dermatitis, asthma, and obesity. Founded in 2006 and based in Newark, California, Protagonist has built its pipeline around peptide-based medicines designed to mimic or block naturally occurring proteins in the body.

Key Fundamentals

EPS1.03
P/E134
ROE12.10
RPS4.36
ROIC46.34
ROA11.29
EBITDA, mln85.88
EV / EBITDA106
EV / EBIT108
Revenue, mln282
EV / Revenue32.34

Quote Details

Last 138.43
Change -1.1 (-0.79%)
Open 136.89
Volume 408,856
Turnover 56,597,932
Average Volume 788,085

Financial Ratios

Pre-Tax Profit Margin30
Leverage Ratio1.05
Current Ratio21.71
Price / Book10.83
Price / Tangible Book10.83
Price / Cash Flow70.12
Price / Free Cash Flow79.43
Debt / Equity0.01
Price / Sales35.20

Financial Strength

Altman Z-Score126
Piotroski F-Score 8 / 9
Beneish M-Score-2.97
Price to Intrinsic Value13.01
Price to Graham Number8.08
1-Year Target Price178.57
Short Ratio13.63
Short % of Float16.78

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week 7.52% 92 / 100   
1 Month 0.79% 74 / 100   
2 Months 3.1% 78 / 100   
6 Months 38.43% 94 / 100   
1 Year 88.34% 96 / 100   



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