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Fulcrum Therapeutics Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 08/03/2026 16:00
Fulcrum Therapeutics Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization273.14 mln
Float48.08 mln
Earnings Date08/05/2026

Piotroski F-Score

3 / 9
Below average

1-Year Forecast

5.83
Exceptional upside

Relative Strength

72 / 100
Outperforming

Debt / Equity

0.02
Debt-free

ROE

-28.75
Deeply negative

Dividend Yield

0.00%
No dividend

Business Description

Fulcrum Therapeutics is a US-based clinical-stage company focused on developing targeted treatments for patients with serious genetic diseases that currently have few or no effective options. Its lead drug candidate, pociredir, works by stimulating the production of fetal hemoglobin and is being tested as a potential treatment for sickle cell disease and beta-thalassemia. The company is also researching treatments for other rare blood and fibrotic conditions, and holds a licensing agreement with CAMP4 covering key compounds and related intellectual property. Founded in 2015 and based in Cambridge, Massachusetts, Fulcrum is working to turn genetic insights into meaningful therapies for underserved patient populations.

Key Fundamentals

EPS-1.21
ROE-28.75
ROIC-738
ROA-27.20
EBITDA, mln-85.18
EV / EBITDA0.92
EV / EBIT0.91

Financial Strength

Piotroski F-Score 3 / 9
1-Year Target Price5.83
Short Ratio2.24
Short % of Float10.50

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week -0.54% 28 / 100   
1 Month -3.39% 32 / 100   
2 Months -52.68% 5 / 100   
6 Months -65.42% 6 / 100   
1 Year -44.87% 16 / 100   



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