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Ionis Pharmaceuticals Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 07/15/2026 16:00
Ionis Pharmaceuticals Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization9,312.54 mln
Float164 mln
Earnings Date08/05/2026

Piotroski F-Score

2 / 9
Weak

Beneish M-Score

-1.28
Manipulation likely

1-Year Forecast

93.23
Transformational upside

Relative Strength

3 / 100
Severely lagging

Debt / Equity

4.15
Highly leveraged

ROE

-60.42
Deeply negative

Business Description

Ionis Pharmaceuticals is a California-based biotech company that develops and sells medicines targeting RNA, a key molecule that carries genetic instructions within the body. The company has several approved treatments on the market for serious conditions including spinal muscular atrophy, hereditary nerve disease, and rare disorders affecting fat metabolism. Ionis also has a broad pipeline of experimental therapies in clinical trials targeting heart disease, liver disease, neurological conditions, and other rare genetic illnesses. To support its research and commercialization efforts, the company works alongside major pharmaceutical partners including GSK, AstraZeneca, Novartis, Roche, and Biogen.

Key Fundamentals

EPS-2.01
ROE-60.42
RPS6.20
ROIC-31.52
ROA-10.34
EBITDA, mln-217
EV / EBITDA-62.34
EV / EBIT-55.97
Revenue, mln1,058
EV / Revenue12.79

Financial Strength

Altman Z-Score2.46
Piotroski F-Score 2 / 9
Beneish M-Score-1.28
1-Year Target Price93.23
Short Ratio8.59
Short % of Float13.99

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week -35.2% 1 / 100   
1 Month -25.31% 7 / 100   
2 Months -25.93% 11 / 100   
6 Months -32.98% 17 / 100   
1 Year 28.63% 76 / 100   



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