| | Astellas Pharma Inc | Drug Manufacturers - General | Healthcare | -8.51 | -3.43 | -8.30 | -1.20 | 5.92 | 45.82 | 47.60 | -10.83 |
| | Astellas Pharma Inc ADR | Drug Manufacturers - General | Healthcare | -1.48 | -2.21 | -10.08 | -12.51 | 3.18 | 36.93 | 32.24 | -18.06 |
| | Bayer AG ADR | Drug Manufacturers - General | Healthcare | 0.39 | 3.24 | -6.34 | -7.70 | -2.77 | 35.33 | 37.52 | -25.11 |
| | Bayer AG | Drug Manufacturers - General | Healthcare | -1.64 | 5.98 | -8.53 | -5.95 | -0.58 | 35.94 | 39.99 | -24.80 |
| | Daiichi Sankyo Co Ltd ADR | Drug Manufacturers - General | Healthcare | -0.62 | -1.61 | -6.57 | -13.00 | -27.98 | -35.53 | -56.78 | -54.78 |
| | GSK Plc | Drug Manufacturers - General | Healthcare | 4.77 | -5.14 | -1.38 | -13.55 | 2.04 | 22.64 | 31.13 | 54.51 |
| | Mayne Pharma Group Ltd | Drug Manufacturers - General | Healthcare | 0.00 | -3.13 | -14.36 | -8.55 | -27.23 | -54.41 | -50.18 | -39.69 |
| | Novo Nordisk A/S Series B | Drug Manufacturers - General | Healthcare | 1.09 | -2.75 | -9.68 | 7.27 | -11.01 | -44.21 | -70.71 | -45.79 |
| | Novartis AG | Drug Manufacturers - General | Healthcare | 0.70 | 0.51 | -1.94 | -11.03 | 13.72 | 23.20 | 42.04 | 52.15 |
| | Otsuka Holdings Co Ltd ADR | Drug Manufacturers - General | Healthcare | -3.59 | -9.83 | -8.90 | 0.85 | 8.42 | 28.80 | 53.36 | 65.10 |
| | Kalbe Farma ADR | Drug Manufacturers - General | Healthcare | 0.00 | 0.00 | -11.86 | -30.28 | -38.96 | -53.59 | -53.14 | -53.14 |
| | Roche Holding AG | Drug Manufacturers - General | Healthcare | -1.74 | -2.91 | -6.89 | -6.30 | -2.62 | 16.19 | 33.66 | 18.73 |
| | Roche Holding AG ADR | Drug Manufacturers - General | Healthcare | -0.63 | 2.16 | -2.30 | -6.28 | 5.17 | 25.38 | 56.22 | 37.02 |
| | Roche Holding AG | Drug Manufacturers - General | Healthcare | 0.55 | -1.32 | -2.88 | -6.14 | 5.03 | 25.45 | 53.63 | 35.50 |
| | Santen Pharmaceutical Co Ltd ADR | Drug Manufacturers - General | Healthcare | 0.68 | 1.52 | 18.31 | 20.76 | 18.14 | 7.68 | 16.06 | 37.30 |
| | Sanofi S.A. | Drug Manufacturers - General | Healthcare | 0.00 | -0.02 | 2.91 | -2.27 | -11.85 | -14.99 | -9.80 | -12.86 |
| | Daiichi Sankyo Co Ltd | Drug Manufacturers - General | Healthcare | -8.27 | -9.39 | -13.60 | -21.20 | -33.87 | -35.88 | -58.41 | -56.44 |
| | Chugai Pharmaceutical Co Ltd ADR | Drug Manufacturers - General | Healthcare | -3.02 | -4.32 | -9.99 | -25.30 | -12.82 | -15.17 | 48.95 | 60.04 |
| | Ono Pharmaceutical Co Ltd ADR | Drug Manufacturers - General | Healthcare | -1.59 | -0.51 | -11.61 | -12.71 | 0.14 | 30.93 | -4.07 | -28.02 |
| | Chugai Pharmaceutical Co Ltd | Drug Manufacturers - General | Healthcare | -2.26 | -0.35 | -9.12 | -25.78 | -12.81 | -8.35 | 55.71 | 60.58 |
| | Cosmo Pharmaceuticals N.V. | Drug Manufacturers - General | Healthcare | -1.46 | -3.73 | -6.75 | -26.50 | -28.04 | 19.81 | -5.42 | 116.52 |
| | CSPC Pharmaceutical Group Ltd ADR | Drug Manufacturers - General | Healthcare | -2.87 | -6.33 | -15.17 | -24.31 | -7.55 | -20.05 | 5.06 | 13.49 |
